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Home >> Specialities >> Liver Transplant >> Liver Cirrhosis

Liver Cirrhosis

Introduction

Cirrhosis of the liver is a late-stage liver disease in which good liver tissue is gradually replaced by scar tissue. This is the outcome of long-term, chronic hepatitis. Hepatitis is a type of liver inflammation that can occur for a variety of reasons. When inflammation persists, your liver attempts to repair itself through scarring. But too much scar tissue inhibits your liver from functioning normally. The final step is chronic liver failure.

Cirrhosis is a degenerative disorder that worsens as scar tissue accumulates. Initially, your body adjusts to compensate for your diminished liver function, which you may not notice. This is referred to as compensated cirrhosis. However, when your liver function declines further, you will start to feel symptoms. This condition is known as decompensated cirrhosis.

Symptoms

The signs and symptoms of cirrhosis vary depending on how advanced the disease is. You may not have any symptoms at all at first, or you may have vague symptoms that are similar to those of other disorders. Cirrhosis symptoms become increasingly obvious as your liver function degrades.

Causes

Cirrhosis is a progressive scarring process caused by chronic inflammation in the liver. Any chronic liver illness that produces chronic hepatitis can progress to cirrhosis. The most common causes include alcohol-induced hepatitis, non-alcoholic steatohepatitis, chronic hepatitis C infection, and chronic hepatitis B infection.

Risk factors

If you are over the age of 50, have a history of frequent alcohol use, have chronic viral hepatitis infection, or have metabolic syndrome, you may be more likely to develop liver cirrhosis.

Diagnosis and Tests

A healthcare physician will initially evaluate you for signs and symptoms of liver cirrhosis. They will ask you when your symptoms began and whether they have changed over time. They will also ask about your medical history, any drugs, herbs, or supplements you take, as well as your diet and lifestyle. They will look for indications that suggest a history of liver disease or injury. They will do extra medical tests to detect evidence of liver cirrhosis. Some of the possible tests include blood tests, imaging studies, and a liver biopsy.

Management and Treatment

Cirrhosis creates permanent scarring in your liver, which cannot be reversed. While your liver has incredible healing abilities in general, cirrhosis is a stage of disease in which it no longer has enough healthy cells to cure itself. However, you may be able to slow or stop cirrhosis from advancing. This is decided by the cause, the amount to which it may be addressed, and your response to the treatment. Treatment for cirrhosis of the liver includes addressing the source, if possible, to halt or diminish the damage, making general diet and lifestyle adjustments to reduce stress on your liver, managing or screening for cirrhosis complications, and, as a last resort, a liver transplant.

Certain forms of liver disease can be treated with drugs, albeit their efficacy varies. Antivirals, for example, are effective in treating chronic hepatitis C but not chronic hepatitis B. Corticosteroids and immunosuppressants can help with some autoimmune conditions, but not all. Other medications can correct the impact of certain genetic illnesses while only addressing the symptoms of others. Toxic or alcohol-induced liver damage can only be repaired by eliminating the toxins from your life. To deal with this, some people may need substance abuse treatment. Controlling metabolic factors such as cholesterol, blood sugar, and obesity can help reduce nonalcoholic liver disease. Some people may need medication to help them manage these issues.

Diet and lifestyle

Even if your liver illness is caused by something else, avoiding alcohol and substances that harm your liver will help you keep it healthier for longer. The same is true for metabolic stress variables. Healthcare specialists advised that anyone suffering from any sort of liver illness try to keep a healthy weight, eat healthy meals, and exercise often. In addition, certain patients may require dietary supplements to address nutritional inadequacy.

Complications

Once your healthcare professional has diagnosed cirrhosis, they will look for common side effects. The most prevalent adverse effect is portal hypertension, which has its own set of issues that require particular treatment. You may require a small treatment to seal a bleeding vein, a blood transfusion to replace blood cell count, kidney dialysis, oxygen therapy, paracentesis and antibiotics for ascites, and laxatives to absorb and eliminate toxins from your gastrointestinal tract.

Prevention

You may be able to prevent liver disease from advancing to cirrhosis by intervening earlier in the process. This is dependent on whether you are aware of it and whether you can take actions to avoid it. Many people may not exhibit symptoms in the early stages, but a normal health exam may help bring it to light. This may provide you the opportunity to make significant adjustments or begin treatment.

Conclusion

Cirrhosis is a severe, progressive liver disease marked by irreversible scarring and reduced liver function. While it can be caused by a variety of factors, including persistent alcohol use, viral hepatitis, and non-alcoholic fatty liver disease, appropriate management and treatment are critical to improving patient outcomes. Early detection and action can help to reduce the disease's course and avoid potentially fatal complications.

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