Book Appt. Call Now
  • Find a doctor
  • Send a query
  • Book an Appointment
  • Second Opinion

Send a Query

Book an Appointment

Ask for a Second Opinion

Home >> Specialities >> Kidney Transplant >> IgA Nephropathy

IgA Nephropathy

IgA Nephropathy is also referred to as Berger's disease. It is marked by the build-up of IgA or immunoglobulin A in the kidneys, which leads to severe inflammation. IgA is a type of protein produced by the immune system that helps fight infections. In patients with IgA nephropathy, the protein accumulates in the kidneys and damages their filtering units, i.e. the glomeruli. Gradually, it leads to scarring and progresses to complete renal failure. 

What causes IgA Nephropathy?
IgA Nephropathy is caused by the build-up of immunoglobulin A in the kidneys. It is not known why this happens; however, there are certain factors that may be linked to it. These are:

  • Faulty genes that run in families
  • Chronic liver diseases like cirrhosis, hepatitis B and hepatitis C
  • Celiac disease, which is triggered by gluten consumption 
  • Chronic infections like HIV

What are the symptoms of IgA Nephropathy?
A patient with IgA Nephropathy may not initially experience any sign or symptom; these tend to develop with time as the condition aggravates. The classic symptoms of the condition are hematuria, i.e. presence of blood in urine, and albuminuria, i.e. the increased amount of albumin in the urine. 
As the condition progresses and leads to kidney failure, the patient may also experience the following:

  • Hypertension
  • Little urine output
  • Swelling in the limbs
  • Fatigue and weakness
  • Drowsiness 
  • Unusual itching 
  • Numbness in different areas of the body
  • Unusual headaches
  • Loss of appetite and weight 
  • Nausea and vomiting
  • Problems related to sleep

Our Doctors

SHALBY Sanar International Hospitals provides extensive medical procedures backed up with our state-of-the-art technology and a team of highly qualified & experienced clinical experts.

Patient Testimonials



Our doctors pen down their research findings and experiences from time to time. Their words provide deep insight into the latest techniques, technologies and other advancements in healthcare. It provides expert answers to all kinds of health questions for real-life issues.


Latest News & Events

Since the day of its foundation, SHALBY Sanar International Hospitals is committed to provide comprehensive healthcare services. It regularly organizes awareness programs in its premises and encourages outdoor healthcare activities and camps with an intent to put focus on preventive healthcare.